Antidepressant Medication Might Be Good For Your Heart

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(Who paid for the study ?  wouldnt surprise me if it was a drugs company)

A study by researchers from the Loyola University Medical Center has revealed that taking certain types of anti depressant medication may have a positive effect on the cardiovascular system.

As people who are suffering from depression are at greater risk from cardiovascular disease, this has got to be good news.

It’s all about serotonin. Serotonin is the ‘feel good’ neurotransmitter and it is already known that serotonin plays a significant role in our moods and in depression.

When a person is depressed, not enough serotonin reaches across the synapse to the postsynaptic cell from the presynaptic cell and too much is taken back in by the presynaptic cell.

A type of antidepressant known as Selective Serotonin Reuptake Inhibitors, or SSRIs, work by inhibiting the reuptake of serotonin by the presynaptic cell so that the postsynaptic cell has a better chance of receiving the serotonin.

Now the researchers have discovered that SSRIs can also slow down the way the blood platelets clump together so could be helpful in conditions such as hardening of the arteries.

The study involved only 50 adults, half of who were taking selective serotonin reuptake inhibitors for depression and half who weren’t.

Blood samples were taken from each of the volunteers at the beginning of the study and then again one month and two months later.

After a month, the researchers treated the platelets with platelet activating substances which would cause the cells to clump together.

What they found was that practically all of the cells clumped together in the blood that was taken from those who weren’t taking SSRIs. The same thing didn’t happen with those who were taking SSRIs, only just over a third of those cells clumped together.

The researchers concluded that the SSRI medication had somehow inhibited or altered platelet’s ability to aggregate. However, the effect also appeared to be temporary.

When the researchers tested the bloods again at the two month point, the platelets of those taking SSRIs clumped together more than they did at the one month point.

The assumption is that SSRIs have a greater impact on platelet clumping earlier on in the treatment, but more research is required in order to establish if this is so.

Consequently, Dr Evangelos Litinas, a researcher in the Center’s pathology department, and his team, extended the study to take more samples after 3 months and will also look at the effects of another type of SSRI.

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